Tuesday April 2nd we didn't have a daily question per se... instead we did a wrap up activity on transcription and translation with the following problems.
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| If you look at the Red line on problem 1 - I changed one nucleotide, which in turn, changed one of the amino acids this is an example of a missense mutation. In the second one, I also changed ONE nucleotide, but this time it would have NO affect on the protein because it still coded for the same amino acid. This is an example of a silent mutation. |
Imagine though that I inserted a nucleotide or deleated one...... THIS is what would happen to the reading frame during tranlsation.
We then wrapped up the translation notes that you needed to finish.
Wednesday
April 3rd
A frameshift mutation early in a gene is most likely to have
which effect on the protein for which the mutated gene codes?
1. The
protein will be silent
2. the
protein will have extensive incorrect amino acid sequences
3. the
protein will perform its function better than a nonmutated copy
4. the
protein will function normally because any changes will be minor
The genetic code is classified as redundant because more than
one codon codes for most amino acids.
This feature of the genetic code makes which type of mutation possible?
1. Silent 2. Nonsense
3. frameshift 4. catastrophic
These two DQ's acted as an introduction to today's notes. While I had you actually go through these types of mutations yesterday, we had not yet written down the notes. I also wanted to make sure that you understood the OVERALL processes of transcription and translation so we worked through the following diagram
This required one extra slide of notes to help you out.
We then went through the following notes on mutations:
